I made a campaign based on that idea.
The thing with AI is that players are always going to be able to game the AI. If you want to do that, then fine, but then what is the point of playing? I see making AI rules for models in Malifaux would be the easiest as you have a deck of cards to work with. My gaming group is pretty small so co op games have always been on my mind. Maybe it is about time to return to my old campaign.