I would have to say that things would be simpler and possibly unbalanced without the Master Shenanigans amplifying/supporting their crews.
Games without Henchmen or Masters would basically mean no SS and certain crews don't do well without their masters. Examples would be Showgirls, Gremlins (maybe not the Kin but not sure), Abominations, Insignificant, and possibly Nightmares. Usually these crews sort of rely/synergize(?) with the play-style of their Master so you may not see them doing well.
The rest of the crews can do well, with the possibility of certain crews going into hyperdrive (Family, Spirits/Undead, Nephilim) or possibly creating new over the top combos for the format.