I haven't played that many games of Malifaux, with Von Schtook or in general, I'm definitely no pro competitive player.
Also, I'm really not familiar with Pandora's crew, so maybe I'll mention things that don't matter so much for Pandora
Anyway here are some thoughts I have :
Von Schtook has a pulse action that gives out focus to transmortis models, and a trigger on one of his attacks that gives him focus as well, so I'm thinking The carver might be quite a pain against transmortis.
It's always worth noting that Von Schtook has an action that enables him to remove any number of conditions on a target, and has a built in trigger that makes the target suffer as much damage as the highest value of one of the removed condition. So you shouldn't rely on stacking one condition on one model (like how Kaeris might want to have a lot of burning on a fire golem for instance).
Also, since Von Schtook can remove any number of conditions on his friendly models, you probably want to spread out negative conditions on several ennemy models rather than "put all your eggs in one basket".
The transmortis crew has a lot of ways to give out the injured condition, which can really help their attack potential.
So you might want to take some condition removal on your crew (I'm not familiar with Pandora, I don't know if her crew has access to condition removal, but you could always get Serena Bowman or take the Eldritch Magic upgrade - which could also be used to remove focus on transmortis models)
I think it's also important to note that Von Schtook's crew can be deceptively fast.
His pulse that gives out focus makes models also push up to 3" (but it's only once per turn), the undergraduates can push models up to 4" (can only do it once on the same model per turn), and Von Schtook can give out fast to models that have an attached upgrade (with a built in trigger of his action that removes condition. Plus he can put upgrades on friendly transmortis models, so if he wants to give fast to a model, he'll be able to).
Also his totem, the research asssitant, gives out +1Mv to models starting their activation near him.
So with 2 undergraduates, one pulse from Schtook, all affecting the same mode, you have 4"+4"+3"=11" inches.
If that model was also given fast, with the +1Mv from the research asssitant, that is one hell of a threat range turn one (especially on the Valedictorian who has flight, and the "on your heels" trigger on her bonus action)
That's all I have for now.
I'm sure some people might have better insight though 😄