I take 2 sorrows, doppel, primordial, and effigy, then either Lust, Lilitu, Widow Weaver as a support piece, and then either Nekima, Hooded, or Bishop as a beater.
Sometimes I swap the beaters out for 2 depleted depending on the strat, because Pandora does so much work on her own with 1-2 sorrows.
Effigy is MONEY with brawler Pandora.