I've never really made a thorough analysis of the difference of the two models but I would assume that what you loose on the ammount of blind packagings sold, you win on people who say "F%$& the blind packaging".
What happens to random games is that people buy retail volumes of them and sell individual pieces on Ebay.
So other than the thrill of "i might get lucky this time" if you really want a particular rare piece, I don't see much of a reason to buy them.
Though there is some scary pattern in what Caffeinated had mentioned.
Btw, isn't AT43 and Confrontation basically following this pattern?