After taking on an Ortega starter with a Pandora starter a couple times now, I offer the following tidbits:
1. Pandora can probably take one round of shooting from Perdita, don't push your luck and try to survive two rounds. Perdita, due to her See the Unseen ability must be your priority. Do whatever it takes to remove her in one round, if at all possible.
2. Because so many of our models have Martyr, it's tempting to clump them together. Beware the Papa Loco suicide run--you don't want to lose your Sorrows to him, you want to use your Sorrows to make Perdita pay for losing those Wp tests (in addition to making her shoot herself, of course).