Model Color uses a latex base, so it's a little soft on the model and can be damaged more easily (it was originally an animation paint). Game Color is a resin base and is more durable. I prefer how the model color flows, it's silkier or something I feel, and I prefer a more naturalistic paint approach so the colors are more appealing to me in Model Color. Also, I feel Game Color can preserve brush strokes while Model Color doesn't. I don't have any problem with the Model Color chipping once I have put a good brush-on matte varnish over the model, though the color does lose some billiance, whereas the Game Color starts much brighter and so varnish brings the color down a bit, but it still satys a bit bright.