Scheduling and regularity were by far the biggest obstacles I’ve faced when trying to start a Through the Breach campaign (or other RPGs for that matter). I’ve tried playing online but I always miss the tactile feel of measuring minis and flipping cards and what not. A solution that worked for my friends and me was to do less of an epic campaign and more of a string of one-shots. I created a secret organization that they all worked for that would send them random jobs in exchange for food, lodging, and not causing the runes carved on their backs to liquify their innards; imagine a Malifaux Suicide Squad. When players can’t make a session, we simply say their handler assigned them to a different task then come up with a short description of what happened so they can still “level up.” If we want to play but someone new will be around, we can throw in a new character and say the handler had to call in a extra help for this mission. While it lacks some of the cliffhanger drama of an epic campaign, it’s helped my group remain consistent in playing, which is what I think matters most.