My players have a none-too-bright beatstick character in our current campaign, and I'm running them through "Night in Rottenburg". Due to a bit of unexpected exploration and improvisation, the Fated found themselves inside one of Barrone's topside labs populated with failed experiments. Towards the back of the room I described an elaborate set of beakers, tubes and refining equipment. The Beatstick, acting true to form, decided to punch the chemistry kit instead of investigating, thus setting off a massive Nitro glycerin fueled explosion that leveled the building they were in and almost dying in the process (but suffered no permanent effects).
Thinking back, I really should have been a bit more severe with the repercussions. Nothing says "Hey, maybe don't punch random test tubes again" like having half your upper torso blown off.