The one thing I can think of is that you pretty much need someone in the group who can take care of Crit effects, especially the Bleeding out condition.
Almost all the Crit effects are pretty balanced, but the bleeding out effect is horrible for players. If you don't have anyone with a high enough doctoring skill, you are dead within a minute, and if the doctor is the one who got it, there's almost no hope of survival, because removing it on yourself is really hard.
That being said, I like the urgency of the effect, I just think it's a bit too hard to remove.
Other than that, I like this system because it's not much that breaks the game, it's really thought through, and fairly well balanced. Sure, some pursuits are stronger than others, but all pursuits seem useful in what they do, so none of them seem underpowered.