I managed to get a victory against Perdita with my Viktorias in my last game (being also the first against them). It is all about the victory points and how to achieve them.
I had Victoria of Blood (with Frame for murder on her) charge into a guild guard without starting this charge in LoS of Perdita (she had that trigger on her). Then, after Perdita killed her with shooting, that was a guaranteed 3 VP.
Next thing, when my Viktoria of Blood died: Killjoy came out and charged into the Perdita Crew with all of his models having activated already (seems like Perdita likes to be last in a round).
That was quite some fun.
Two Ronins kept two guild guards and the Perdita Gunslinger busy, dying only slowly with defensive stance and everything.
Important is that you also look at your own crew and see, what might be important to you, what he wants to see dead and how to make him pay for it.